Current Clinical Trials
The Boxer Lab is currently running numerous clinical trials at the UCSF Memory and Aging Center, approximately half treating Alzheimer’s disease (AD) and the other half treating frontotemporal dementias (FTD), including progressive supranuclear palsy (PSP). There is quite a lot of overlap between both the symptoms and the underlying biology of AD and FTD, and several of the investigational drugs are being tested in both diseases.
The main biological targets for these drugs are the proteins amyloid beta and tau. Both of these proteins become misfolded and dysfunctional during disease, clumping together in “plaques” or “tangles” and ultimately causing brain cells to die. Amyloid beta plaques are characteristic of AD, while tau tangles afflict AD and FTD. Click on the links to learn more about these proteins and other therapeutic targets, or go to the clinicaltrials.gov page for each trial below.
New trials are always launching, so if you don’t see one that fits what you’re looking for, check back in a month or two. You may also contact us at [email protected]